VACCINE DOSE:-

It is NOT true that a small breed of puppy should receive a smaller vaccine dose than puppies of larger breeds. All puppies regardless of age, body weight, breed, and gender are given the same vaccine dose. Vaccines are generally administered in one milliliter (cc) doses. Simply follow the manufacturer's recommendations. To administer a lesser vaccine amount than recommended will likely result in insufficient immunity.

TIME TO PRODUCE PROTECTION:-

Vaccines do not stimulate immunity immediately after they are administered. Once a vaccine is administered, the antigens must be recognized, responded to, and remembered by the immune system. In most puppies, disease protection does not begin until five days post vaccination. Full protection from a vaccine usually takes up to fourteen days. In some instances, two or more vaccinations several weeks apart must be given to achieve protection. In general, modified live vaccines and those vaccines administered intranasally provide the fastest protection.

Why do some vaccinated animals still get the disease?

It is a fact that in the USA today, literally hundreds and perhaps thousands of vaccinated dogs and cats are still contracting the diseases they were vaccinated against. Some term this 'vaccine failure,' although it is more likely a failure of the immune system to respond than a problem with the vaccine itself.

Parvovirus is a serious case in point. How can a puppy get the disease and possibly die if it was vaccinated? Unfortunately, for some reason the vaccine did not stimulate the immune system enough to protect the puppy from disease. The reason may be interfering maternal antibodies, the vaccines themselves, the dog's own immune system, or genetics. By far, the most common reason in puppies is interfering maternal antibodies.